WEST LAFAYETTE, Ind. -- Senior center A.J. Hammons led five players in double figures with 16 points and eight rebounds Thursday night, and No. 22 Purdue rallied from a three-point halftime deficit to defeat Ohio State 75-64 in Mackey Arena.

After Ohio State (12-8, 4-3) pulled to within 62-61 on a Trevor Thompson free throw with 2:51 remaining, the Boilermakers (17-3, 5-2) closed the game on a 13-3 run, which included a key 3-pointer from sophomore point guard P.J. Thompson, who had 12 points.

Sophomore forward Vince Edwards had 12 points and seven rebounds for Purdue, freshman forward Caleb Swanigan finished with 10 points and 10 rebounds and sophomore center Isaac Haas also scored 10.

Jae'Sean Tate led Ohio State with 17 points and 10 rebounds, guard Kam Williams scored 14 -- all in the first half -- and guard A.J. Harris scored 10.

Purdue's size was the deciding factor on a night when the Boilermakers made only 4 of 17 shots from 3-point range, but the inside game carried Purdue to victory.

Purdue Ied it at 48 on Rapheal Davis' driving layup with 11:20 remaining. The Boilermakers seized a 53-52 lead on freshman Ryan Cline's 3-pointer with 9:02 to play.

Two free throws from Edwards, two free throws from Thompson and a Thompson 3-pointer with 6:16 left gave Purdue a 60-54 lead, capping a 10-2 run.

Ohio State made 6 of 9 attempts from 3-point range and got a combined 23 points from Williams and Tate to lead 36-33 after 20 minutes. The Boilermakers were 0 of 8 from beyond the arc in the opening half.

Purdue stayed close by making 9 of 13 free throws while Ohio State made 4 of 5. The Boilermakers enjoyed a 19-16 first-half rebounding advantage, but the Buckeyes enjoyed a 23-8 edge in points from non-starters with Williams and guard A.J. Harris combining for 21 off the bench.

Hammons had 10 first-half points for Purdue, which shot only 35.3 percent (12 of 34). Ohio State was 13 of 25 (52 percent) during the opening half.

Purdue used an 11-2 run to capture a 29-28 lead on an Edwards dunk with 3:07 left in the half, but Williams sank consecutive 3-pointers to give the Buckeyes a 34-29 lead, giving him 14 at intermission.

Purdue got two free throws from P.J. Thompson and Hammons' fifth first-half field goal to stay within striking distance.

The Buckeyes got eight quick points from Williams, including two 3-pointers, and the Buckeyes expanded their lead to 24-18 with?7:45?left in the opening half.

NOTES: Although Ohio State is only 17-26 all-time in Mackey Arena entering Thursday's the Buckeyes' 17 victories are the most by an opponent in the venue, which opened in Dec. 1967 ... Before Thursday, Ohio State was 7-1 against the Boilermakers in the past eight meetings and led the series 89-84 ... Ohio State freshman G JaQuan Lyle ranks second nationally among all freshmen in assists with 99 ... Purdue senior G Rapheal Davis is one of 30 being considered for the Senior Class Award, which honors community, classroom, character and competition excellence. Davis is the reigning Big Ten Defensive Player of the Year ... Fans attending Thursday's game received either a white or volt t-shirt and were asked to wear it as a sign of support for Purdue's Center for Cancer Research ... The Boilermakers lead the Big Ten in field goal percentage defense (36.4).