Temple 76, North Carolina State 72: Khalif Wyatt hit the clinching free throws with 2.1 seconds left and led the way with 31 points as the ninth-seeded Owls held off the Wolfpack in the second round of the NCAA Tournament at Dayton, Ohio.

Jake O’Brien added 18 points and Rahlir Hollis-Jefferson scored 12 for Temple (24-9), which will play No. 1 seed Indiana in the third round on Sunday. The Owls are attempting to reach the Sweet Sixteen for the first time since 2001.

Lorenzo Brown scored 22 points, C.J. Leslie had 20 and Richard Howell collected 14 points and 15 rebounds, but North Carolina State (24-11) lost its opening game in the NCAA Tournament for the first time since 2003.

Temple held a 38-22 lead at the half and led by as much as 18 in the second half before the Wolpack began to chip away. North Carolina State chopped it to single digits three times before Wyatt gave the Owls their last double-digit edge on a 3-pointer with 4:41 left that made it 62-51.

Leslie responded with a 3-pointer and Wood buried two in a 9-1 run to pull within 63-60 with 3:09 to play. Wyatt and Leslie traded free throws to keep it a three-point gap, but Lorenzo Brown missed a 3-point attempt that would have tied it and Temple went 11-of-14 from the free throw line in the final 1:27 to close it out.

GAME NOTEBOOK: North Carolina State outshot (55.8 percent to 48 percent) and outrebounded (34-24) Temple, but the Owls only committed five turnovers to the Wolfpack’s 13. … Wyatt was fighting through an injury to his left hand but went 12-of-14 from the free throw line to make up for a 9-of-22 effort from the floor. … North Carolina State went 4-of-13 from 3-point range.